Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
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Graphene insole OEM factory Taiwan
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.One-stop OEM/ODM solution provider Indonesia
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Graphene insole manufacturer in Vietnam
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Ergonomic insole ODM production factory Taiwan
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene-infused pillow ODM China
Bald eagles and other wildlife in the southern United States have been facing a mysterious neurodegenerative disease since the 1990s. New research links the cause to a toxin produced by cyanobacteria on invasive aquatic plants, potentially exacerbated by herbicides used to control these plants. Mysterious Eagle Deaths Traced to Toxin Bald eagles, as well as other wildlife, have been succumbing to a mysterious neurodegenerative disease in the southern United States since the 1990s. New research by the Martin Luther University Halle-Wittenberg (MLU) in Germany and the University of Georgia, USA, identifies the cause of these deaths: a toxin produced by cyanobacteria that grow on invasive aquatic plants. The problem is potentially exacerbated by herbicides used to control those plants. The results were published in Science. In 1994, bald eagles were dying on a mass scale in the U.S. state of Arkansas. The animals were losing control over their bodies, and holes were developing in their brains. A previously unknown neurodegenerative disease, termed vacuolar myelinopathy (VM), was identified. “The origin of the disease was a complete mystery,” says Professor Timo Niedermeyer from the Institute of Pharmacy at MLU. Link to Invasive Aquatic Plant and Cyanobacteria Later on, American researchers found that not only eagles were affected, but also their herbivorous prey. The scientists discovered a connection to an invasive aquatic plant (Hydrilla verticillata) that grows in freshwater lakes in the affected regions. However, there were still some lakes with the aquatic plant where the disease was not manifesting. In 2005 Susan B. Wilde, a professor at the Warnell School of Forestry and Natural Resources at the University of Georgia, identified a previously unknown cyanobacterium on the leaves of Hydrilla verticillata, which appeared to be the cause of the disease. It turned out that vacuolar myelinopathy only occurs in places where the cyanobacterium colonizes the invasive plant. She called the bacterium “eagle killer that grows on Hydrilla”: Aetokthonos hydrillicola. Bacterial colonies of the cyanobacterium A. hydrillicola growing on a leaf of the invasive aquatic plant H. verticillata. Credit: Susan Wilde “I stumbled across a press release issued by the university in Georgia and was fascinated by these findings, because I’ve worked with cyanobacteria for years,” says Niedermeyer. He had samples sent to him, cultivated the bacteria in the laboratory, and sent them back to the U.S. for further testing. But the tests came back negative: The bacteria from the lab did not induce the disease. “It’s not just the birds that were going crazy, we were too. We wanted to figure this out,” says Niedermeyer. Once again, he had colonized leaves sent to him. Steffen Breinlinger, a doctoral student in his research group, then used a new imaging mass spectrometer to investigate the composition on the surface of the plant’s leaf, molecule by molecule. He discovered a new substance that only occurs on the leaves where the cyanobacteria grow, but is not produced in the cultivated bacteria. Proof of the Toxin’s Role in Eagle Deaths His investigations into the chemical structure of the isolated molecule showed that it contains five bromine atoms. “The structure is really spectacular,” says Breinlinger. The properties are unusual for a molecule formed by bacteria. And they provide an explanation for why the toxin did not form under laboratory conditions. Standard culture media in which cyanobacteria grow do not contain bromide. “We then added bromide to our lab cultures, and — the bacteria started producing the toxin,” says Breinlinger. Wilde and her colleagues tested the isolated molecule in birds, and finally, after almost a decade of research in the Wilde and Niedermeyer labs, they had the proof: the molecule does trigger VM. According to the name of the bacterium, the researchers call their discovery aetokthonotoxin, “poison that kills the eagle.” “Finally, we did not only catch the murderer, but we also identified the weapon the bacteria use to kill those eagles,” says Wilde. Bald Eagle flying. A research group participating in the study from the Czech Academy of Sciences also found sections of DNA containing genetic information for the synthesis of the new molecule. Why the cyanobacteria form the toxin on the aquatic plants in the first place, however, has yet to be studied. One of the herbicides used to combat the invasive aquatic plant might play a crucial part in VM occurrence: It contains bromide and thus might stimulate toxin production. The neurological disease has not yet occurred in Europe, and no instance of the toxin-forming cyanobacterium has been reported. Reference: “Hunting the eagle killer: A cyanobacterial neurotoxin causes vacuolar myelinopathy” by Steffen Breinlinger, Tabitha J. Phillips, Brigette N. Haram, Jan Mare, José A. Martínez Yerena, Pavel Hrouzek, Roman Sobotka, W. Matthew Henderson, Peter Schmieder, Susan M. Williams, James D. Lauderdale, H. Dayton Wilde, Wesley Gerrin, Andreja Kust, John W. Washington, Christoph Wagner, Benedikt Geier, Manuel Liebeke, Heike Enke, Timo H. J. Niedermeyer and Susan B. Wilde, 26 March 2021, Science. DOI: 10.1126/science.aax9050 The research has been supported by the Deutsche Forschungsgemeinschaft (German Research Foundation, DFG), the Czech Science Foundation GACR, the US Department of Interior, US Fish and Wildlife Service, the Florida Fish & Wildlife Conservation Commission, the Gulf States Marine Fisheries Commission, the National Institute of Food and Agriculture McIntire-Stennis Capacity Grant and the American Eagle Foundation.
Researchers at the Instituto Gulbenkian de Ciência (IGC) have discovered that zebrafish, like humans, require oxytocin to mirror the emotions of others, a phenomenon known as emotional contagion. The zebrafish’s recognition of and reaction to emotions within their group, their use of similar brain areas to humans for this process, and their oxytocin-regulated behavior make them an ideal model for understanding emotional contagion, its impact on well-being and society, and its potential applications in various fields. According to a recent study, fish copy emotions just like humans. And the responsible molecule is oxytocin. When an individual flashes a smile at us, it’s natural for us to reciprocate with a similar expression. Conversely, if we’re in the company of someone experiencing anger or stress, we often inadvertently adopt these negative feelings. This innate inclination to mirror the emotional states of those around us is known as emotional contagion. This rudimentary empathy has been wired into our brains over millennia, and its purpose is fairly straightforward. When danger is present, emotional contagion helps disseminate fear rapidly, thereby enhancing our likelihood of survival. Furthermore, echoing the feelings of others aids in forging meaningful social connections. But this behavior is not exclusive to humans. New data from the Instituto Gulbenkian de Ciência (IGC) confirm that the mechanisms we use to synchronize emotions go back to the most ancient group of vertebrates, fish. In their most recent work, the IGC team led by Rui Oliveira tried to understand if, similarly to humans and other mammals, zebrafish need oxytocin to adopt others’ emotions. The experiments they carried out showed that, when fish similar to those found in nature see a shoal in distress, they mirror their behavior. On the other hand, fish with genetic alterations either on oxytocin or its receptors keep swimming normally even when they see their conspecifics in distress. This shows that this molecule is necessary to spread fear, for instance, when one of the shoal’s members is hurt. But how can we be sure that fish are recognizing fear in their conspecifics and not simply copying their behavior? “We realized these observers approach the distressed shoal even when it gets back to swimming normally, whereas mutated fish prefer to be close to the group that had always been in a neutral state”, explains Kyriacos Kareklas, a postdoc at the IGC and co-first author of the paper. This means that, via oxytocin, zebrafish decode and mimic the emotional state behind the neighboring shoal’s movements and start behaving in a similar way. It is impressive that fish get close to the distressed shoal, given that, in nature, this could mean that a predator is nearby. Although it puts them at risk “being approached by conspecifics could help the group recover from stress”, the researcher clarifies. These other-oriented acts are well-described in mammals, where they are also regulated by oxytocin. But oxytocin is not the only common factor between fish and humans regarding emotional contagion. “To recognize and match emotions, zebrafish use areas of the brain that are equivalent to some of those that humans also use for this purpose”, the principal investigator Rui Oliveira explains. This makes these fish the perfect model to study this social behavior and its neural mechanisms. This way, these findings lead the way towards understanding how we are affected by others’ emotions and how this shapes our well-being and society, with implications that go from public health and politics to marketing. Reference: “Evolutionarily conserved role of oxytocin in social fear contagion in zebrafish” by Ibukun Akinrinade, Kyriacos Kareklas, Magda C. Teles, Thais K. Reis, Michael Gliksberg, Giovanni Petri, Gil Levkowitz and Rui F. Oliveira, 23 March 2023, Science. DOI: 10.1126/science.abq5158
Sumatran rhino Kertam on the island of Borneo. Credit: Ben Jastram, Leibniz-IZW In an effort to save the endangered Sumatran rhino species from extinction, a team from the Max Delbrück Center has successfully grown stem cells and mini-brains from the skin cells of Kertam, the last male Sumatran rhino in Malaysia who died in 2019. The team’s goal is to use these cells to create sperm cells for reproductive efforts. The Sumatran rhinoceros, the world’s smallest and most ancient rhino species, was once widely distributed throughout East and Southeast Asia. However, poaching and habitat destruction have severely reduced the population, with only a few dozen individuals remaining in the rainforests of Sumatra and the Indonesian portion of Borneo. The rarity of these remaining individuals makes mating encounters increasingly scarce, contributing to the species’ endangered status. The Last of Their Kind in Malaysia The Sumatran rhinoceros, which is the only surviving rhino species with hair, has been considered extinct in Malaysia since 2019 following the death of male Kertam and, just a few months later, female Iman. But a team of Berlin scientists led by Dr. Vera Zywitza and Dr. Sebastian Diecke, head of the Pluripotent Stem Cells Platform at the Max Delbrück Center in Berlin, are not content with this. They and their international partners have an ambitious goal: to turn skin cells taken from now-deceased Sumatran rhinos into stem cells, from which they can then derive egg and sperm cells to be used in assisted reproduction – in this case, fertilization in the laboratory. The embryos bred in the petri dish, which will be the offspring of Kertam and other already deceased or infertile individuals, will be carried to term by surrogate rhino mothers. Pictured here is a one-month-old brain organoid of a rhinoceros. In this microscopic cross-sectional image, progenitor cells of neurons can be seen in red. Fully developed neurons are colored green. Credit: Silke Frahm-Barske, Max Delbrück Center In the scientific journal iScience, the team led by first author Zywitza and last author Diecke has now reported an initial success: they have generated induced pluripotent stem cells, or iPS cells for short, from Kertam’s skin samples. These cells have two key advantages. First, they are able to divide infinitely and therefore never die; and second, they are able to transform into any cell type in the body. For their recently published study, the group has already grown brain organoids, also called “mini-brains,” from Kertam’s iPS cells. Learning From the White Rhino The technology platform developed its stem cell technologies as part of the BioRescue research project for the even more critically endangered northern white rhinoceros – of which only two females now remain, living in a Kenyan wildlife reserve. “Our current study has benefited a lot from the knowledge gained through this large-scale project, which is funded by the German Federal Ministry of Education and Research,” says Zywitza. Professor Thomas Hildebrandt, head of the Reproduction Management Department at the Leibniz Institute for Zoo and Wildlife Research (IZW) in Berlin, and his research group were also significantly involved in the project. Zywitza recounts how all those involved in the current study were surprised and pleased to discover that the methods used to turn the skin cells of northern white rhinos into stem cells also worked well with the cells of Sumatran rhinos. Under the microscope, the stem cells of both rhino species were barely distinguishable from human iPS cells. Nevertheless, there were species-specific differences: “In contrast to northern white rhino iPS cells, Kertam’s iPSCs could not be cultivated without feeder cells, which release growth factors that help to keep stem cells in a pluripotent state,” explains Zywitza. A Deeper Look Into Evolution In addition to preserving the species, the stem cells obtained from Kertam’s skin could serve another purpose: “iPS cells from exotic animals provide a unique tool to gain insights into the evolution of organ development,” says Zywitza. To demonstrate this, Dr. Silke Frahm-Barske, who is also a scientist in Diecke’s research group, grew brain organoids from the cells. “To the best of our knowledge, mini-brains like these have only been obtained from mouse, human, and non-human primates so far,” says Frahm-Barske. “So we were very pleased to see that the stem cells we generated from the Sumatran rhino formed organoids quite similar to those of humans.” However, she added that the team had to treat the human and rhino iPS cells slightly differently in order to generate the brain organoids. The Next Step is Sperm Cells The team’s next goal is to use Kertam’s iPS cells to grow sperm suitable for artificial insemination. “This step is more difficult,” says Zywitza. “To obtain sperm cells, we first need to use the iPS cells to cultivate primordial germ cells – the precursors of eggs and sperm.” This is the tricky task the scientists are now going to tackle. They also plan to obtain iPS cells from other Sumatran rhinos. Reproduction expert Thomas Hildebrandt explains why efforts like these are necessary: “Measures are indeed being taken in Indonesia to preserve the Sumatran rhino population by bringing together the remaining individuals in wildlife reserves,” he says. “But females that have not been pregnant for a long time often become infertile, for example, due to cysts that develop on their reproductive organs, or they may just be too old to bear young.” “Even though our work is attempting to make the seemingly impossible possible – i.e., to ensure the survival of animals that would otherwise probably disappear from our planet – it must remain an exception and not become the rule,” emphasizes Zywitza. “Despite all the buzz around what we are doing in the lab, this can at best make a small contribution to saving these rhinos from extinction. The protection and conservation of the animals’ few remaining habitats is at least equally important.” Reference: “Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros” by Vera Zywitza, Silke Frahm, Norman Krüger, Anja Weise, Frank Göritz, Robert Hermes, Susanne Holtze, Silvia Colleoni, Cesare Galli, Micha Drukker, Thomas B. Hildebrandt and Sebastian Diecke, 18 November 2022, iScience. DOI: 10.1016/j.isci.2022.105414
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