Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
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Innovative pillow ODM production solution in Taiwan
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.China high-end foam product OEM/ODM
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.China insole ODM for global brands
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Taiwan insole ODM service provider
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Indonesia graphene product OEM service
Immunofluorescent staining shows expression of the new SARS-CoV-2 Spike-receptor LRRC15 (green) in post-mortem lung tissue section from individual with COVID-19. Credit: The University of Sydney The protein receptor found in the lungs sticks to the virus and pulls it away from the target cells. University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body. This protein, the leucine-rich repeat-containing protein 15 (LRRC15), is an inbuilt receptor that binds the SARS-CoV-2 virus without passing on the infection. The research opens up an entirely new area of immunology research around LRRC15 and offers a promising pathway to develop new drugs to prevent viral infection from coronaviruses like COVID-19 or deal with fibrosis in the lungs. The study was published on February 9, 2023, in the journal PLOS Biology. It was led by Professor Greg Neely with his team members Dr. Lipin Loo, a postdoctoral researcher, and PhD student Matthew Waller at the Charles Perkins Centre and the School of Life and Environmental Sciences. Pastel pop art illustration of human lung generated using OpenAI’s DALL·E 2. Instructions used to generate this image were “a pastel pop art painting of the human anatomy with the lungs colorful and bright.” Credit: OpenAI’s DALL·E 2/Greg Neely The University study is one of three independent papers that reveal this specific protein’s interaction with COVID-19. “Alongside two other groups, one at Oxford, the other at Brown and Yale in the USA, we found a new receptor in the LRRC15 protein that can stop SARS-CoV-2. We found that this new receptor acts by binding to the virus and sequestering it which reduces infection,” Professor Neely said. “For me, as an immunologist, the fact that there’s this natural immune receptor that we didn’t know about, that’s lining our lungs and blocks and controls virus, that’s crazy interesting. “We can now use this new receptor to design broad-acting drugs that can block viral infection or even suppress lung fibrosis.” What Is LRRC15? The COVID-19 virus infects humans by using a spike protein to attach to a specific receptor in our cells. It primarily uses a protein called the angiotensin-converting enzyme 2 (ACE2) receptor to enter human cells. Lung cells have high levels of ACE2 receptors, which is why the COVID-19 virus often causes severe problems in this organ of infected people. Like ACE2, LRRC15 is a receptor for coronavirus, meaning the virus can bind to it. But unlike ACE2, LRRC15 does not support infection. It can, however, stick to the virus and immobilize it. In the process, it prevents other vulnerable cells from becoming infected. Immunofluorescent staining shows expression of the new SARS-CoV-2 Spike-receptor LRRC15 (green) in post-mortem lung tissue section from an individual with COVID-19. Credit: The University of Sydney “We think it acts a bit like Velcro, molecular Velcro, in that it sticks to the spike of the virus and then pulls it away from the target cell types,” Dr. Loo said. “Basically, the virus is coated in the other part of the Velcro, and while it’s trying to get to the main receptor, it can get caught up in this mesh of LRRC15,” Mr. Waller said. LRRC15 is present in many locations such as lungs, skin, tongue, fibroblasts, placenta and lymph nodes. But the researchers found human lungs light up with LRRC15 after infection. “When we stain the lungs of healthy tissue, we don’t see much of LRRC15, but then in COVID-19 lungs, we see much more of the protein,” Dr. Loo said. “We think this newly identified protein could be part of our body’s natural response to combating the infection creating a barrier that physically separates the virus from our lung cells most sensitive to COVID-19.” Implications of the Research “When we studied how this new receptor works, we found that this receptor also controls antiviral responses, as well as fibrosis, and could link COVID-19 infection with lung fibrosis that occurs during long COVID,” Mr. Waller said. “Since this receptor can block COVID-19 infection, and at the same time activate our body’s anti-virus response, and suppress our body’s fibrosis response, this is a really important new gene,” Professor Neely said. “This finding can help us develop new antiviral and antifibrotic medicines to help treat pathogenic coronaviruses, and possibly other viruses or other situations where lung fibrosis occurs. “For fibrosis, there are no good drugs: for example, idiopathic pulmonary fibrosis is currently untreatable.” Fibrosis is a condition in which lung tissue becomes scarred and thickened, causing breathing difficulties. COVID-19 can cause inflammation and damage to the lungs, leading to fibrosis. The authors said they are developing two strategies against COVID-19 using LRRC15 that could work across multiple variants – one which targets the nose as a preventative treatment, and another aimed at the lungs for serious cases. The researchers also said that the presence or lack of LRRC15, which is involved in lung repair, is an important indication of how severe a COVID-19 infection might become. “A group at Imperial College London independently found that absence of LRRC15 in the blood is associated with more severe COVID, which supports what we think is happening.” Dr. Loo said. “If you have less of this protein, you likely have serious COVID. If you have more of it, your COVID is less severe. “We are now trying to understand exactly why this is the case.” The research involved screening human cell cultures for genes and investigating the lungs of human COVID-19 patients. Reference: “Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs” by Lipin Loo, Matthew A. Waller, Cesar L. Moreno, Alexander J. Cole, Alberto Ospina Stella, Oltin-Tiberiu Pop, Ann-Kristin Jochum, Omar Hasan Ali, Christopher E. Denes, Zina Hamoudi, Felicity Chung, Anupriya Aggarwal, Jason K. K. Low, Karishma Patel, Rezwan Siddiquee, Taeyoung Kang, Suresh Mathivanan, Joel P. Mackay, Wolfram Jochum, Lukas Flatz, Daniel Hesselson, Stuart Turville and G. Gregory Neely, 8 February 2023, PLOS Biology. DOI: 10.1371/journal.pbio.3001967 Funding: National Health and Medical Research Council, New South Wales Government, Australian Government
Scientists propose that ancient human reproductive behavior and the female menstrual cycle were aligned with the moon but have been largely disrupted by modern lifestyles and artificial light. Women’s menstrual cycles sometimes align with lunar cycles, likely influenced by moonlight and gravity. The blog “Ladyplanet. Natürlich Frau sein” is quite certain: “Our cycle is linked to that of the moon. The most obvious connection is the length of the two cycles,” it says. The newspaper “Berliner Tagesspiegel” comes to the opposite conclusion: “The length of women’s menstrual cycles is an average value, for some it lasts longer, for others it is shorter. Even the same woman can have cycles of different lengths. If they really were connected to the lunar cycle, all women would have their fertile days at the same time,” the paper’s knowledge section reads. So what is true? A team led by Würzburg chronobiologist Charlotte Förster has now used scientific methods to examine the connection between lunar and women’s menstrual cycles. The result: The scientists hypothesize that in ancient times human reproductive behavior and the female menstrual cycle were synchronous with the moon but that our modern lifestyles and artificial light have largely changed this synchrony. Förster holds the Chair of Neurobiology and Genetics at the University of Würzburg (JMU). The results of her study have now been published online in the journal Science Advances. Correlation Between Moon Phases, Pregnancy and Birth Rate “We know many animal species in which the reproductive behavior is synchronized with the lunar cycle to increase reproductive success,” says Charlotte Förster. Since the menstrual cycle of women is similar in length to the lunar cycle with its approximately 29.5 days, a connection seems likely. This is also supported by a number of other findings: For example, several older studies show that women whose cycles are in sync with that of the moon have the highest probability of becoming pregnant. Two large longitudinal studies demonstrate a significant correlation between birth rate and lunar phase with a slight increase in birth rate at full moon and a corresponding decrease at new moon. Recent evidence also suggests that births are more likely to occur at night during a full moon and during the day when there is a new moon. To clarify the influence of the moon on human reproduction, Förster and her colleagues from Munich, Buenos Aires, and the USA studied the course of the menstrual cycles of 22 women who had kept menstrual diaries — in some cases over a period of 32 years. “To our knowledge, this approach to analyzing this type of long-term data has not been used before,” Förster says. Instead, previous studies had analyzed large numbers of women in their entirety, combining results from different women, age groups, years, and seasons. The Moon Orbits Earth in Several Cycles The team correlated the records of each of the 22 women with the lunar cycle. Whereas “lunar cycle” is actually an unacceptable simplification. “Scientifically speaking, the moon exhibits three distinct cycles that periodically change its luminance and the gravity with which it impacts Earth,” Förster says. On the one hand, there is the change between full moon and new moon which takes place on average every 29.53 days with slight variations. Secondly, the moon does not go around Earth in a fixed orbit. Instead, its position varies relative to the equator. Sometimes it is more to the north, sometimes more to the south. This cycle lasts 27.32 days. The third cycle is a little longer with an average of 27.55 days. It results from the fact that the moon accompanies Earth on an elliptical orbit and is accordingly sometimes closer, sometimes further away. All of these cycles affect the intensity of the moonlight and gravity, which can be seen in the tides, for example. In addition, they interact with each other and can lead to special constellations at longer intervals, producing special phenomena, such as a solar eclipse, which is part of a regular cycle where the darkening of the sun repeats about every 18 years. Moonlight Is the Strongest Clock Generator “All three lunar cycles influence the onset of menstruation in women”: This is the conclusion the scientists draw after evaluating the records of the study participants. The nightly moonlight seems to be the strongest clock synchronizer, but the gravitational forces of the moon also contribute to the effect. Of course: Not all women follow the change of light and dark in the night sky and if they do, usually only for certain periods of time. On average, in women under 35 years of age, menstruation occurs synchronously with the full moon or new moon in just under a quarter of the recorded time. For women over 35, this is the case on average in barely one tenth of the time. The synchronism of lunar and menstrual cycle does not only decrease with increasing age: It also seems to decrease to the extent that women are exposed to artificial light sources at night. Typical “night owls,” who go to bed late and leave the lights on longer, show no obvious synchronization with the moon. A Sense of Gravity According to the scientists, the fact that synchronization occurs only sporadically and that the courses of women’s menstrual cycles vary suggests that the moon’s light-dark cycle alone is not a strong synchronizing factor of menstruation. They have the first evidence that gravity also influences the monthly cycles. “In the second halves of 1961, 1979, 1997, and 2015, the menstrual cycles of seven out of nine women were synchronous with the change of full moon and new moon,” says Charlotte Förster. This interval of 18 years corresponds exactly to the rhythm in which the three lunar cycles combine to produce very special constellations. This conjunction may have enhanced the moon’s strength as a clock generator. The observation that gravity sets a rhythm for humans could explain why certain cycles, such as menstruation but also sleep onset and sleep duration, are temporarily linked to either the full moon or the new moon: In both phases the influence of the moon’s gravity on Earth is similar. Effects of gravity could also explain a study’s observation that both sleep onset and sleep duration of college students are in sync with the lunar cycle — even though they live in Seattle, a city that is so bright at night that moonlight is barely perceptible. For Förster and her colleagues, all these observations suggest that the human organism can respond not only to rapid changes in gravity, as perceived by the equilibrium system, but also to slow, periodically recurring gravitational changes. However, the scientists are aware of the limited significance of their study due to the relatively small number of women studied. Her hopes are therefore pinned on the use of technology that is both simple and modern: a mobile phone app. This will make it possible to study the relationship between menstrual and lunar cycles and the influence of artificial light on a large number of women around the world. Reference: “Women temporarily synchronize their menstrual cycles with the luminance and gravimetric cycles of the Moon” by C. Helfrich-Förster, S. Monecke, I. Spiousas, T. Hovestadt, O. Mitesser and T. A. Wehr, 27 January 2021, Science Advances. DOI: 10.1126/sciadv.abe1358
A cross-section of biocrust taken by confocal scanning laser microscopy. Soil particles are visible as various shades of gray, while the bundles of cyanobacterial filaments (fluorescent red) are situated between them. Credit: Penn State Researchers report that a new method for assessing microbial activity in wetted soil leads to a better understanding of vulnerability. Using a novel method to detect microbial activity in biological soil crusts, or biocrusts, after they are wetted, a research team led by Penn State has gleaned insights in a recent study that illuminate the crucial role microbes play in forming a living skin over many semi-arid ecosystems around the world. The tiny organisms — and the microbiomes they create — are threatened by climate change. The researchers recently published their findings in the journal Frontiers of Microbiology. “Biocrusts currently cover approximately 12% of Earth’s terrestrial surface, and we expect them to decrease by about 25% to 40% within 65 years due to climate change and land-use intensification,” said team leader Estelle Couradeau, Penn State assistant professor of soils and environmental microbiology. “We hope this work can pave the way to understanding the microbial functions supporting biocrust resilience to the rapidly changing climate patterns and more frequent droughts.” Biological soil crusts are assemblages of organisms that form a perennial, well-organized surface layer in soils. They are widespread, occurring on all of the continents wherever a shortage of water limits the growth of common plants, allowing light to reach bare soil. But there is still sufficient water to support the growth of microorganisms that perform valuable ecosystem services such as taking carbon and nitrogen from the air and fixing them in the soil, recycling nutrients and holding soil particles together, which helps prevent dust. Penn State graduate student Ryan Trexler collects cores of biocrust from the field before bringing them back to the lab to study. Credit: Penn State That soil-stabilizing function — which reduces erosion by providing the means for soil to clump and not break down into dust — is extremely important, according to Couradeau. Her research group, now in Penn State’s College of Agricultural Sciences, has been intensively studying biocrusts for a decade. “Most dust is generated in drylands, and studies suggest that the presence of biocrusts in drylands greatly reduce the amount of dust that would otherwise make its way into the atmosphere,” she said. “We think losing biocrusts would cause a 5% to 15% increase in global dust emission and deposition — which would affect the climate, environment, and human health.” Microbial Adaptation to Drylands In the semi-arid regions where biocrusts exist, the organisms — tiny mosses, lichens, green algae, cyanobacteria, other bacteria, and fungi — may experience just a few rain or snow events a year, explained Ryan Trexler, a doctoral degree candidate in the Intercollege Graduate Degree Program in ecology and in biogeochemistry, who spearheaded the research. “When the soil is dry, for the most part, the microbes in the soil are dormant, not doing much,” he said. “But as soon as they sense water, they’re resuscitated very quickly, within seconds to minutes. And they are actively making chlorophyll and fixing carbon and nitrogen until the soil is dry again — and then the microbes go dormant again. They go through cycles of activity every time it rains.” A view of the Colorado Plateau near Moab, Utah, where biocrust samples were taken in the fall following rain that wetted the soil sufficiently to activate the microbes. Credit: Penn State To study biocrusts, the researchers took samples from three plots of undisturbed, cyanobacteria-dominated biocrusts located on the Colorado Plateau near Moab, Utah. Biocrust samples were taken in the fall following rain that wetted the soil sufficiently to activate the microbes. The samples were subsequently dried and stored in the dark and then rewetted much later in the research. “We sampled what we call ‘a cold desert,’ because it’s very arid, but in the winter, it sometimes snows,” Trexler said. “So, it’s not as hot as many other arid places, but still plants cannot thrive there because there’s not enough water. And so, the only community that we find in soils at the site are microbial.” A Cutting-Edge Approach to Microbial Research To determine which microorganisms are active within soil communities, the researchers coupled bioorthogonal non-canonical amino acid tagging — known as BONCAT — with fluorescence-activated cell sorting. BONCAT is a powerful tool for tracking protein synthesis on the level of single cells within communities and whole organisms, while fluorescence-activated cell sorting sorts cells based on whether they are producing new proteins. The researchers combined these processes with shotgun metagenomic sequencing, which allowed them to comprehensively sample all genes in all organisms present in biocrust samples. They applied this method to profile the diversity and potential functional capabilities of both active and inactive microorganisms in a biocrust community after being resuscitated by a simulated rain event. The researchers found that their novel approach can discern active and inactive microorganisms in wetted biocrusts. Reference: “BONCAT-FACS-Seq reveals the active fraction of a biocrust community undergoing a wet-up event” by Ryan V. Trexler, Marc W. Van Goethem, Danielle Goudeau, Nandita Nath, Rex R. Malmstrom, Trent R. Northen and Estelle Couradeau, 26 June 2023, Frontiers in Microbiology. DOI: 10.3389/fmicb.2023.1176751 The active and inactive components of the biocrust community differed in species richness and composition at both four hours and 21 hours after the wetting event, the researchers reported. Contributing to the research were Marc Van Goethem, Lawrence Berkeley National Laboratory, and King Abdullah University of Science and Technology, Jeddah, Saudi Arabia; Danielle Goudeau, Nandita Nath, Trent Northen, and Rex Malmstrom, Lawrence Berkeley National Laboratory, U.S. Department of Energy Joint Genome Institute. The U.S. Department of Energy supported this research.
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